Huining Chai

Education: Ph.D. (Dalian Institute of Chemical Physics, Chinese Academy of Sciences (CAS))

Major/Department: Environmental Science

Position: Associate Professor

Email: huiningchai@163.com

Employment rack（工作履历）

2019.8—now, Associate Professor, School of Environmental and Municipal Engineering, Qingdao University of Technology

2018.3—2019.7, Research Associate, Institute of Materia Medica, Shandong First Medical University and Shandong Academy of Medical Sciences

Professional service（学术兼职）

1. Member of the Chinese Chemical Society and Biophysical Society of China

2. Reviewer of ACS Appl. Bio Mater., Progress in Chemistry.

Research field（研究领域）

1. Biomimetic synthesis of Micro/Nanomaterials

2. Catalysis and Environmental analysis of nanomaterials

Research project（科研项目）

2019.1-2021.12, the National Natural Science Foundation of China (Nos. 21801158).

2020.8-2022.07, Qingdao Postdoctoral Applied Research Project (Nos. 2020036).

2019.11-2021.11, Open Project Fund of Qingdao University of Technology (Nos. QUTSEME201934).

2020.12-2022.12, State Key Laboratory of Bio-Fibers and Eco-Textiles (Qingdao University, Nos. KF2020201).

Academic achievements（学术成果）

SCI Journal Paper

[1] K. Yu, M. Li, H. Chai, Q. Liu, X. Hai, M. Tian, L. Qu, T. Xu, G. Zhang*, X. Zhang, MOF-818 nanozyme-based colorimetric and electrochemical dual-mode smartphone sensing platform for in situ detection of H₂O₂ and H₂S released from living cells. Chem. Eng. J., 2023, 451, 138321.

[2] A. Boakye, K. Yu, B. K. Asinyo, H. Chai, T. Raza, T. Xu, G. Zhang, L. Qu, A Portable Electrochemical Sensor Based on Manganese Porphyrin-Functionalized Carbon Cloth for Highly Sensitive Detection of Nitroaromatics and Gaseous Phenol, Langmuir 2022, DOI: 10.1021/acs.langmuir.2c01908.

[3] G. Zhang, Y. Ma, H. Chai*, K. Yu, Y. Li, S. Wang, J. Ma, L. Qu, W. Tan*, X. Zhang, Porphyrinic metal–organic framework@alumina nanocomposite fluorescent probe: Two-stage stimuli-responsive behavior and phosphate sensing, Sens. Actuators B Chem. 2022, 370, 132395.

[4] G. Zhang*, K. Yu, B. Zhou, J. Wang, C. Zheng, L. Qu, H. Chai*, X. Zhang, Magnetic zirconium-based Prussian blue analog nanozyme: Enhanced peroxidase-mimicking activity and colorimetric sensing of phosphate ion, Microchim. Acta, 2022, 189, 220.

[5] K. Yu, G. Zhang*, H. Chai, L. Qu, D. Shan, X. Zhang*, Two-stage ligand exchange in Mn(III)-based porphyrinic metal−organic frameworks for fluorescence water sensing, Sens. Actuators B Chem. 2022, 362, 131808.

[6] Y. Bai, H. Chai, L. Zhou, G. Jiang, G. Zhang*, Recent Advances on DNAzyme-Based Biosensors for Detection of Uranyl, Front. Chem. 2022, 10, 882250.

[7] M. Li, G. Zhang*, A. Boakye, H. Chai*, L. Qu*, X. Zhang, Recent Advances in Metal-Organic Framework-Based Electrochemical Biosensing Applications, Front. Bioeng. Biotechnol. 2021, 9, 797067.

[8] T. Yan, G. Zhang*, H. Chai, L. Qu*, X. Zhang, Flexible Biosensors Based on Colorimetry, Fluorescence, and Electrochemistry for Point-of-Care Testing, Front. Bioeng. Biotechnol. 2021, 9, 753692.

[9] G. Y. Zhang*, M. J. Li, K. Yu, H. N. Chai*, S. H. Xu, T. L. Xu, L. J. Qu, X. J. Zhang*, Two-Dimensional Metalloporphyrinic Framework Nanosheet-Based Dual-Mechanism-Driven Ratiometric Electrochemiluminescent Biosensing of Protein Kinase Activity, ACS Appl. Bio Mater. 2021, 4, 1616–1623.

[10] G. Y. Zhang*, H. N. Chai, M. W. Tian, S. F. Zhu, L. J. Qu, X. J. Zhang*, Zirconium-Metalloporphyrin Frameworks-Luminol Competitive Electrochemiluminescence for Ratiometric Detection of Polynucleotide Kinase Activity, Anal. Chem. 2020, 92, 7354-7362.

[11] H. N. Chai *, G. Y. Zhang, W. Q. Tan*, J. P. Ma, A robust NNP-type ruthenium(II) complex for alcohols dehydrogenation to esters and pyrroles. Appl. Organometal. Chem. 2020, 34, e5367.

[12] H. N. Chai *, K. Yu, B. Liu, W. Q. Tan, G. Y. Zhang, A Highly Selective Manganese-Catalyzed Synthesis of Imines under Phosphine-Free Conditions. Organometallics, 2020, 39, 217.

[13] H. N. Chai *, W. Q. Tan, Y. Y. Lu, G. Y. Zhang*, J. P. Ma, Sustainable synthesis of quinolines (pyridines) catalyzed by a cheap metal Mn(I)-NN complex catalyst. Appl. Organometal. Chem. 2020, 34, e5685.

[14] H. N. Chai, T. T. Liu, Q. F. Wang, Z. K. Yu,* Substituent Effect on the Catalytic Activity of Ru(II) Complexes Bearing a Pyridyl-Supported Pyrazolyl-Imidazolyl Ligand for Transfer Hydrogenation of Ketones. Organometallics 2015, 34, 5278-5284.

[15] H. N. Chai, Q. F. Wang, T. T. Liu, Z. K. Yu,* Diruthenium(II)-NNN Pincer Complex Catalysts for Transfer Hydrogenation of Ketones. Dalton Trans. 2016, 45, 17843-17849.

[16] H. N. Chai, T. T. Liu, Z. K. Yu,* NHTs Effect on the Enantioselectivity of Ru(II) Complex Catalysts Bearing a Chiral Bis(NHTs)-Substituted Imidazolyl-Oxazolinyl-Pyridine Ligand for Asymmetric Transfer Hydrogenation of Ketones. Organometallics 2017, 36, 4136-4144.

[17] H. N. Chai, T. T. Liu, D. Y. Zheng, Z. K. Yu,* Cooperative N-H and CH₂-Skeleton Effects on the Catalytic Activities of Bimetallic Ru(II)-NNN Complexes: Experimental and Theoretical Study. Organometallics 2017, 36, 4268-4277.

[18] H. N. Chai, L. D. Wang, T. T. Liu, Z. K. Yu,* A Versatile Ru(II)-NNP Complex Catalyst for the Synthesis of Multisubstituted Pyrroles and Pyridines. Organometallics 2017, 36, 4936–4942.

[19] Q. F. Wang^#, H. N. Chai^#, Z. K. Yu,* Acceptorless Dehydrogenation of N-Heterocycles and Secondary Alcohols by Ru(II)-NNC Complexes Bearing a Pyrazoyl-Indolyl-Pyridine Ligand. Organometallics 2018, 37, 584-591.

Patent

1. 一种双阶段刺激-响应型的卟啉MOF@氧化铝纳米复合物荧光探针用于磷酸根的检测（China patent）

2. 吡啶基桥联NNP钴配合物及其应用（China patent）

3. 吡啶基桥联吡唑类金属锰催化剂及其应用（China patent）